About The Course
Welcome Message

Welcome to the CoursePlus Web site for PRINCIPLES OF IMMUNOLOGY I (260.611.01), a course offered by the Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health.

Course Description

Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.

Course Learning Objectives

Upon successfully completing this course, students will be able to:

  • Define the tissue, cellular and molecular components that constitute the vertebrate innate and adaptive immune system
  • Explain the generation of lymphocyte antigen receptors and the molecular and cellular basis for diversity and specificity of receptors on immune cells
  • Define the basis for antigen presentation to T cells
  • Define the basis for recognition of self and non-self recognition
  • Define the development and survival of lymphocytes
  • Explain the major signaling pathways used by immune cells
  • Define T cell-mediated and B cell-mediated immunity

Course Time

Tue Thu   8:30 AM to 10:20 AM

Course Faculty

A course in advanced biology

Grading Policy & Grading Restrictions

Grading Policy: Student evaluation based on mid-term and final exams.

Grading Restrictions: Letter grade

Administrative Contact