120.602.01 | AY 2012-2013 - 1st Term | 4 Credit(s)
TTh 1:30:00 PM
  • Contact Information
    Michael Matunis
  • Course Learning Objectives

    Upon successfully completing this course, students will be able to:

    • Explain the molecular mechanisms underlying key biological processes
    • Describe genome structure, gene regulation, and cell cycle control
  • Course Description
    Discusses synthesis of macromolecules, the genetic code, regulation of gene expression, and recent advances in biotechnology, emphasizing special contributions from microbial studies and cell-free systems.
  • Methods of Assessment
    Student evaluation based on two exams.

    Additional Faculty Notes:

    Each exam accounts for 50% of final grade (final = exam 1 + exam 2 divided by 2) 

    The second exam covers only material discussed in the second half of the class.

  • Prerequisites
    Introductory biochemistry or consent of instructor
  • Required Text(s)

    Additional Faculty Notes:

    Molecular Biology:  Genes to Proteins,  Fourth edition

    Burton E. Tropp

    Jones and Bartlett Learning

  • Course Schedule

    Please see the course Session for a full list of dates and items for this course.

  • Academic Ethics Code

    Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.

  • Welcome Message

    Classes meet on Tuesdays and Thursdays from 1:30-2:50 in room W4030 in the School of Public Health.

  • Course topics

    Bacterial genes and DNA structure, DNA replication, DNA repair, Bacterial transcription, Genetic code and protein synthesis, Genetics and model organisms, Structure of eukaryotic genes, Regulation of eukaryotic gene expression, RNA splicing and processing, micro-RNAs, Molecular basis of cancer, Recombinant DNA technologies


  • Disability Support Services
    If you are a student with a documented disability who requires an academic accommodation, please contact the Office of Student Life Services at 410-955-3034 or via email at