Course Learning Objectives
Upon successfully completing this course, students will be able to:
- Discuss the complex relationships between host and vector that affect transmission and control
- Integrate the host and parasite relationships to Discuss the immune response, nature of disease, and disease manifestations
- Interpret epidemiological indices associated with patterns of malaria transmission
- Evaluate different approaches to malaria control through vector control, chemotherapy, and vaccines when they become available
- Describe the differences between the various species of Plasmodium affecting humans
Course DescriptionPresents issues related to malaria as a major public health problem. Emphasizes the biology of malaria parasites and factors affecting their transmission to humans by anopheline vectors. Topics include host-parasite-vector relationships; diagnostics; parasite biology; vector biology; epidemiology; host immunity; risk factors associated with infection, human behavior, chemotherapy, and drug resistances; anti-vector measures; vaccine development; and management and policy issues.
Methods of Assessment
Student evaluation based on mid-term take-home and final exams.
Additional Faculty Notes:
The midterm is a take home exam covering the first 9 lectures to be turned in on April 30th, a Tuesday. The midterm will be released on April 23.
The final will be a in class short answer test on all concepts covered in the course on May 16.
The midterm will count 50% of the grade as well as final.
Additional Faculty Notes:
Suggested but not required textbooks:
Essential Malariology Edited by David A. Warrell and Herbert M. Gilles
Malaria Molecular and Clinical Aspects Edited by Mats Wahlgren and Peter Perlmann
Malaria: Drugs, Disease and Post-genomic Biology Edited by D.J. Sullivan and S. Krishna
Textbooks are available at library or online bookstores new or used.
Please see the course Session for a full list of dates and items for this course.
Tues March 26 Sullivan Overview and Biology of Parasite Thurs March 28 Shiff Malaria epidemiology Tues April 2 Zavala Immunity to malaria Thurs April 4 Ockenhouse Immunopathogenesis Tues April 9 Sullivan Chemotherapy Nyunt Malaria in Pregnancy/HIV Thurs April 11 Sullivan Malaria diagnosis and laboratory Tues April 16 Hall Malaria Vaccines Thurs April 18 Shiff Malaria control Tues April 23 Shiff Elimination Harvey Behavior change interventions for malaria control Thurs April 25 Malaria Day Tues April 30 Norris Malaria Entomology Thurs May 2 Dimopoulos Genomic Analyses of Anopheles-Plasmodium Interactions Dinglasan MALERA Tues May 7 Sullivan Drugs for malaria control Prigge Targets for new drugs Thurs May 9 Jacobs Lorena Genetic approaches malaria control Smith Modeling elimination Tues May 14 Plowe Drug resistance and Pop genetics Thurs May 16 Final exam in class
Academic Ethics Code
Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.
Welcome to MALARIOLOGY (260.656.01) an advanced course for people interested in a broad up-todate picture of malaria, the disease, its transmission, its biology and control. It is presented by faculty in MMI and guest experts.
Room W2030 Tuesday and Thursday from 3:30 to 5:20 PM.
Overview and Biology of Parasite; Chemotherapy; Immunopathogenesis; Drug resistance and Pop genetics; Malaria epidemiology; Immunity to malaria; Malaria Vaccines; Malaria diagnosis; Targets for new drugs; Malaria in Pregnancy/HIV; Behavior change interventions for malria control; Malaria Entomology and Insecticide resistance; Mosquito population biology; Genomic Analyses of Anopheles-Plasmodium Interactions; Modeling Malaria control; GIS and malaria risk factors; Malaria Eliminition and the Research Agenda
David Sullivan, MD
Office: E5628 BSPH
Tel: 410 502 2522
Home Page: http://faculty.jhsph.edu/Default.cfm?faculty_id=681
Upon completion of this course students will • Understand the complex relationships between host and vector that affect transmission and control. • Integrate the host and parasite relationships to understand the immune response, nature of disease and disease manifestations. • Interpret epidemiological indices associated with patterns of malaria transmission. • Evaluate different approaches to malaria control, either through vector control, chemotherapy and vaccines when they become available. • Understand the differences between the various species of Plasmodium affecting humans.
Disability Support ServicesIf you are a student with a documented disability who requires an academic accommodation, please contact Betty H. Addison in the Office of Student Life Services: firstname.lastname@example.org, 410-955-3034, or 2017 E. Monument Street.