260.664.01 | AY 2012-2013 - 4th Term | 2 Credit(s)
MF 2:00:00 PM
  • Contact Information
    George Dimopoulos
    Douglas Norris
  • Course Learning Objectives

    Upon successfully completing this course, students will be able to:

    • Discuss a variety of molecular entomology research topics
    • Evaluate disease control strategies based on molecular entomology approaches
    • Design basic approches for controling vector borne diseases
  • Course Description
    Provides a broad perspective on the molecular biology of insects and a specific focus on aspects relating to the transmission of insect-borne diseases. Also provides an introduction to insect physiology, developmental biology, genomics and molecular evolution and ecology. Includes several modules addressing molecular mechanisms implicated in insect – host and insect - pathogen interaction, which are essential for disease transmission. Provides background information on essential methodologies used in molecular entomological research and discusses the importance of molecular entomology for the development of disease control strategies. The basic developmental, genetic and genomic focused modules utilize the wealth of knowledge gained from studies in the model insect organism Drosophila, while modules focusing on insects’ role in disease transmission focus on the mosquito vector of malaria Anopheles.
  • Intended Audience
    M.Sc and Ph.D students with background in molecular biology.
  • Methods of Assessment
    Two evaluations will be applied in this course: one short paper and one discussion on specific topics.

    Additional Faculty Notes:
    Grading is based on cource participation and interaction during lectures, a take-home problem set, an essay/proposal and final presentation.

  • Prerequisites
    Students with a background in molecular biology or biochemistry.
  • Required Text(s)

    Additional Faculty Notes:
    This course is based on presentation of diverse molecular entomology topics with accompanying review articles, to be posted on CoursePlus

  • Course Schedule

    Please see the course Session for a full list of dates and items for this course.

  • Academic Ethics Code

    Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.

  • Course topics

    Date : Lecturer : Topic

    MO 3/24: GD, Introduction to molecular entomology

    FRI 3/28: RD, Tsetse-trypanosome interactions

    MO 3/31: GD, Mosquito immunity

    FRI 4/4: CB, Mosquito responses to Plasmodium & fitness impact of immune response.

    MO 4/7: JR, Insect endosymboints as tools for disease control

    FRI 4/11: DO, Genetic drive and sexing

    MO 4/14: JV, Sandfly interactions with Leishmania

    FRI 4/18: GD, Chemosensory reception

    MO 4/21: DN, Molecular ecology / population biology

    FRI 4/25: MJL, Drosophila development

    MO 4/28: DN, Molecular ecology / population biology

    FRI 5/2: CM, Drosophila as a model for visual transduction

    MO 5/5: GD, Project Presentations

    FRI 5/9: MJL, Malaria control through mosquito manipulation

    MO 5/12: NC, Transposable elements



    CB: Dr. Carolina Barillas – Mury, NIAID/NIH

    NC: Dr. Nancy Craig, JHMI

    GD: Dr. George Dimopoulos, JHSPH

    RD: Dr. Rhoel Dinglasan, JHSPH

    MJL: Dr. Marcelo Jacobs-Lorena, JHSPH

    CM: Dr. Craig Montell, JHMI

    DN: Dr. Doug Norris, JHSPH

    JR: Dr. Jason Rasgon, JHSPH

    JV: Dr. Jesus Valenzuela, NIH/NIAID


  • Disability Support Services
    If you are a student with a documented disability who requires an academic accommodation, please contact the Office of Student Life Services at 410-955-3034 or via email at