340.670.11 | AY 2013-2014 - Summer Inst. Term | 2 Credit(s)
MTWThF 9:00:00 AM
  • Contact Information
    Dani Margaret Fallin
    Priya Duggal
  • Course Learning Objectives

    Information not required for this course type

  • Course Description
    This course will cover designs and methods for genetic epidemiology studies of unrelated individuals. Several population genetics concepts relevant to understanding genetic epidemiology designs and statistical tools will be introduced including concepts of quantitative and qualitative traits, genetic risk models, allele/haplotype frequency estimation, and migration/admixture. Methods for the evaluation of single and multiple genetic loci in the context of direct and indirect (linkage disequilbrium) associations with human disease will then be addressed, with examples from genome-wide, candidate gene and sequencing approaches. Methods for gene-gene and gene-environment interaction assessment will also be presented. The lecture material will be supplemented with examples using public and simulated data and currently available free software.

    Additional Faculty Notes:

    This is designed to be a beginner course for those with little genetic epidemiology background.  Unfortunately, we will not be able to cover more advanced topics in this one-week course.

    (15 CME credits, 1.5 CEUs, 2 Acad. credits)*

  • Intended Audience
    Summer Institute students and interested degree-seeking students within the school.

    Additional Faculty Notes:
    Students and professionals with experience in either epidemiology, medicine, genetics, or biostatistics.

  • Methods of Assessment
    Short Exam and in class polls

    Additional Faculty Notes:

    Pass / Fail based on class participation.

    Credit-earning students will take 20-minute quiz

  • Prerequisites
    Basic knowledge of epidemiology and biostatistics
  • Required Text(s)

    Additional Faculty Notes:

    No texts are required. Instructive papers and books will be suggested in class.

  • Course Schedule

    Please see the course Session for a full list of dates and items for this course.

  • Files from the Online Library
  • Academic Ethics Code

    Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.

  • Course topics

    Hardy-Weinberg equilibrium

    linkage disequilibrium

    genetic association analysis

    population stratification



  • Contact Information(from old syllabus)

    Mandy Li, MS


    Priya Duggal, PhD

    Daniele Fallin, PhD

  • Disability Support Services
    If you are a student with a documented disability who requires an academic accommodation, please contact the Office of Student Life Services at 410-955-3034 or via email at