415.611.92 | AY 2013-2014 - 1st Term | 2 Credit(s)
Th 4:30:00 PM
  • Contact Information
  • Course Learning Objectives

    Upon successfully completing this course, students will be able to:

    • Discuss basic structure and function of chromosomes and genes
    • recognize inheritance patterns in pedigrees and assess risks
    • Discuss when and how screening and diagnostic tests are performed and how to interpret results of such tests
    • discuss basic mechanisms of mutation and how mutations can lead to disease
    • Discuss how the inheritance pattern of a disease is determined by the molecular mechanisms by which mutations alter gene function and cause the disease
    • discuss the features of common genetic diseases seen in genetic counseling practice, including natural history and management
  • Course Description

    415.610 addresses the chromosomal basis of heredity, chromosomes and genes, tools of human molecular genetics, single gene inheritance, variation, polymorphism and mutation, genes in populations and genes in families. 415.611 presents the role of genetic counseling in health care and emphasizes the essential components of prenatal, pediatric, and adult genetics services. Indications for referral and genetics education and counseling components are illustrated using care examples. Clinical skills and tools are taught including family, medical and development history taking and pedigree construction. Additional case management skills such as the choice of laboratory and test interpretation, and issues in billing and reimbursment of genetic counseling services are addressed. 415.612 -613 expand on the previous two courses to examine the Hemoglobinapathics and Thalassemias as models of molecular pathology, the molecular/biochemical basis of genetic disease, genetics of cancer, gene mapping

  • Intended Audience

    ScM in Genetic Counseling students.

  • Methods of Assessment

    Grading Policy: Student evaluation based on class participation and problem sets.

    Grading Restrictions: Letter grade

  • Prerequisites


  • Academic Ethics Code

    The code, discussed in the Policy and Procedure Memorandum for Students, March 31, 2002, will be adhered to in this class:

    Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.

  • Disability Support Services

    If you are a student with a documented disability who requires an academic accommodation, please contact Betty H. Addison in the Office of Student Life Services:, 410-955-3034, or 2017 E. Monument Street.