340.641.01 | AY 2013-2014 - 2nd Term | 4 Credit(s)
TTh 1:30:00 PM
  • Contact Information
    Aaron Milstone
    Trish Perl
  • Course Learning Objectives

    Upon successfully completing this course, students will be able to:

    • Introduce the principles of counting/identifying healthcare-associated infections, organisms resistant to antimicrobial agents, or organisms that are epidemiologically important
    • review their epidemiology, and the risk factors for developing colonization and infection
    • Review the data supporting important infection control and antibiotic management strategies for the types of infections and for certain epidemiologically important organisms
    • Effectively respond to questions about exposure to communicable diseases and appropriate prevention and control strategies
    • Explain the impact that healthcare associated infections have on patient safety
  • Course Description
    Introduces the history, descriptive epidemiology, surveillance methods, and economics of exploration of the most important factors influencing nosocomial infections, especially those in pediatric and adult services. Describes and analyzes methods for control of nosocomial infection, including primary and secondary interventions. Also discusses alternative interventions and parallels between contemporary and traditional approaches in developing countries.

    Additional Faculty Notes:

    The history, descriptive epidemiology, and surveillance methods of healthcare associated infections will be discussed in this introductory course. Unique factors relating to epidemiology and infection prevention control in this setting will be discussed including: outbreak investigation, epidemiologically significant organisms, patient safety, prevention strategies and associated economic factors. An in-depth exploration of the most important factors influencing healthcare associated infections in pediatric and adult services and disaster planning will be presented. Methods for control of healthcare associated infections, including primary and secondary interventions, will be described and analyzed. Students will be required to demonstrate their grasp of the subject material through three take-home exercises. Students will design and implement a class project related to healthcare epidemiology at the Johns Hopkins Hospital.

  • Intended Audience
    students interested in infectious disease, prevention, and control in a hospital setting
  • Methods of Assessment
    Student evaluation based on mid-term and final exams, and a paper.

    Additional Faculty Notes:

    Three take Home Exercises-20% each.

    Participation in Class Project-20%.

    Class Participation and Attendance 20%.


  • Course Schedule

    Please see the course Session for a full list of dates and items for this course.

  • Files from the Online Library
  • Academic Ethics Code

    Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.

  • Welcome Message

    The course directors are Drs. Trish Perl and Aaron Milstone. Dr. Perl is the Senior Epidemiologist for the Johns Hopkins HealthSystem.  Dr. Milstone is the Associate Hospital Epidemiologist at JHH and responsible for Infection Control at the Johns Hopkins Childrens Center.  The TA for this course is Rebecca Pierce (

  • Contact Information(from old syllabus)

    Aaron Milstone, MD, MHS
    Tel: 410-614-3917

    Trish Perl, MD, MSc
    Office: United States
    Tel: 410 502 9617

    Trish Perl, MD, MSc
    Office: JHH Osler 425
    Tel: 410-955-8384

  • Course Objectives(from old syllabus)
    *Apply advanced knowledge from epidemiology, microbiology, and immunology to the identification, prevention, and control of healthcare associated infections *Manage resources to provide a humane and cost-effective environment that promotes achievement of optimal host defenses against infection *Evaluate changes in the health care setting to reduce the risk of healthcare associated infections *Demonstrate expertise in healthcare associated infection prevention and control *Identify researchable problems related to healthcare associated infections *Critique clinical practices and policies with regard to their impact on preventing and controlling infections
  • Disability Support Services
    If you are a student with a documented disability who requires an academic accommodation, please contact the Office of Student Life Services at 410-955-3034 or via email at