260.717.01 | AY 2013-2014 - 4th Term | 3 Credit(s)
TTh 9:00:00 AM
  • Contact Information
    Noel Rose
    Fidel Zavala
    Ross McFarland
    Location: CMSC 8-122
  • Course Learning Objectives

    Upon successfully completing this course, students will be able to:

    • Survey the structure of the immune system, the molecular and cellular bases of immune recognition, the effecter functions and regulation of the immune response
    • Relate the function of the immune system to its applications in protection, transplantation and immunological diseases
    • Critically review articles in recent literature
  • Course Description
    Presents advanced topics concerning the immunologic system; the cellular basis of the immune response; effector functions of antibody, lymphocytes, and macrophages; regulation of the immune response; and immunologic diseases. Lectures and readings develop a well-rounded view of the interrelated elements comprising the immune system.
  • Methods of Assessment

    Student evaluation based on class participation and an essay. As this is a discussion class attendence is mandatory and the primary component of the participation grade.

    Additional Faculty Notes:

    Student Presentation and Class Participation (25%)

    Guidelines for Student Presentations

    The presentation will take the form of a journal critique on an article provided by the guest lecturer of the day.  Students will be assigned presentation topics and dates during the first week of class.  The first student presentation will be in class on Thursday, March 27th, and will continue each class until the end of term.  Depending on the class size, some students may be assigned multiple presentations.  Presentations should not exceed 5-7 minutes followed by an additional 2-3 minutes of questions.  Please consider the following when designing your presentations

    1) Purpose of investigation (ie: the questions being asked)

    2) Experimental approach (ie: materials and methods, briefly)

    3) Principal findings (related to the question being asked, focus on the take-home message, not specific details!)

    4) Conclusions

    5) Critique (strengths, weaknesses, etc)

    Please address any questions to Ross McFarland (


    Final Paper (75%)

    Proposals Due: Tuesday Apri 22, 2014.

    Final Draft Due: Thursday, May 15, 2014 (Final Day of Class)

    Guidelines for Literature Critique

    The final paper should be a critical analysis of your chosen subject related to the course material.  A proposal will be submitted three weeks prior to the final due date to make sure you're on the right track.  The proposal should take the form of an abstract describing the subject matter that will be the subject of your critical analysis. 


    Proposal: typed, double-spaced, 11 or 12 point font only.  Length should be approximately 250 words.

    Final Paper: typed, double-spaced, and 11 or 12 font only. Length should be between 8-15 pages excluding title page and references.

    Don't 'stress' on the paper and the fact that is is worth 75% of the final grade.  Craft your paper as a 'critical analysis' of your subject, and you will do fine on the paper.

  • Prerequisites
    260.611-612, ME260.709, ME340.703, or consent of instructor
  • Required Text(s)

    Additional Faculty Notes:

    There are no required textbooks for this course.

    However, reference/supplementary reading includes the following:

    Paul's Fundamental Immunology (5th Edition), Raven Press

  • Course Schedule

    Please see the course Session for a full list of dates and items for this course.

  • Academic Ethics Code

    Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.

  • Course topics

    Unit I: Immune Recognition

    Unit II: Immunology of Inflammation and Infection

    Unit III: Regional Immunology

    Unit IV: Applications of Immunology

  • Contact Information-With general course questions, please first contact TA(

    Dr. Bream                      

    Dr. Cihakova                 

    Dr. Cox                           

    Dr. Detrick                            

    Dr. Dimopoulos             

    Dr. Drake                        

    Dr. Griffin                         

    Dr. Kupfer                        

    Dr. Lamichhane              

    Dr. Levitskaya                  

    Dr. Peterson                     

    Dr. Raimondi                    

    Dr. Rose                            

    Dr. Scott                             

    Dr. Soloski                          

    Dr. Zavala                          

  • Disability Support Services
    If you are a student with a documented disability who requires an academic accommodation, please contact the Office of Student Life Services at 410-955-3034 or via email at