120.606.01 | AY 2013-2014 - 4th Term | 3 Credit(s)
TTh 10:30:00 AM
  • Contact Information
    Jiou Wang
    Valeria Culotta
  • Course Learning Objectives

    This course will prepare you to be able to do the following:

    • Describe the basics for how cells sense and respond to a wide variety of cellular stress agents and maintain fitness and survival through quality control.
    • Understand the basis for state-of-the-art laboratory approaches to research the molecular and cellular biology of stress and quality control.
    • Gain an appreciation of cutting edge research conducted at JHU on cellular stress and quality control.
  • Course Description
    Examines stress sensing and response pathways at the DNA, RNA, and protein levels, covering transcriptional regulation, RNA processing, and protein quality control. Also discusses Organelle-specific stress responses at the level of the endoplasmic reticulum and mitochondria are also discussed. Disseminates course material through formal lectures and discussions of literature. Local JHU scientists highlight each topic by presenting ongoing laboratory research, a “meet the expert” opportunity.
  • Intended Audience
    Ph.D and master students geared towards laboratory research
  • Methods of Assessment
    This course is evaluated as follows: 40% mid-term exam, 50% final exam and 10% class participation.
  • Prerequisites
    Students should have a background of undergraduate or graduate level coursework in Molecular Biology.
  • Course Schedule

    Please see the course Session for a full list of dates and items for this course.

  • Academic Ethics Code

    Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.

  • Disability Support Services
    If you are a student with a documented disability who requires an academic accommodation, please contact the Office of Student Life Services at 410-955-3034 or via email at