MOLECULAR BIOLOGY OF CELLULAR STRESS AND QUALITY CONTROL Syllabus
Course Learning Objectives
This course will prepare you to be able to do the following:
- Describe the basics for how cells sense and respond to a wide variety of cellular stress agents and maintain fitness and survival through quality control.
- Understand the basis for state-of-the-art laboratory approaches to research the molecular and cellular biology of stress and quality control.
- Gain an appreciation of cutting edge research conducted at JHU on cellular stress and quality control.
Examines stress sensing and response pathways at the DNA, RNA, and protein levels, covering transcriptional regulation, RNA processing, and protein quality control. Also discusses Organelle-specific stress responses at the level of the endoplasmic reticulum and mitochondria are also discussed. Disseminates course material through formal lectures and discussions of literature. Local JHU scientists highlight each topic by presenting ongoing laboratory research, a “meet the expert” opportunity.
Ph.D and master students geared towards laboratory research
Methods of Assessment
Grading Policy: This course is evaluated as follows: 40% mid-term exam, 50% final exam and 10% class participation.
Grading Restrictions: Letter grade
Students should have a background of undergraduate or graduate level coursework in Molecular Biology.
Academic Ethics Code
The code, discussed in the Policy and Procedure Memorandum for Students, March 31, 2002, will be adhered to in this class:
Students enrolled in the Bloomberg School of Public Health of The Johns Hopkins University assume an obligation to conduct themselves in a manner appropriate to the University's mission as an institution of higher education. A student is obligated to refrain from acts which he or she knows, or under the circumstances has reason to know, impair the academic integrity of the University. Violations of academic integrity include, but are not limited to: cheating; plagiarism; knowingly furnishing false information to any agent of the University for inclusion in the academic record; violation of the rights and welfare of animal or human subjects in research; and misconduct as a member of either School or University committees or recognized groups or organizations.
Disability Support Services
If you are a student with a documented disability who requires an academic accommodation, please contact Betty H. Addison in the Office of Student Life Services: firstname.lastname@example.org, 410-955-3034, or 2017 E. Monument Street.